Legend of Zelda, The: Twilight Princess
The best way to play Twilight Princess is Dusklight a PC port of the 2001 Gamecube decompilation. It is touted as a very feature-complete port with many QoL improvements.
✔ Multiple platforms supported
✔ Dynamic screen ratio/resolutions (8K+)
✔ Uncapped framerates
✔ Gyro support
✔ Texture pack support
✔ Custom control binds
✔ QoL
✔ Mirrored visuals option to match the Wii release
– Built-in (unofficial) achievements
– Requires a Gamecube NTSC ISO of Twilight Princess
✘ Missing extra Wolf Link amiibo dungeon of 2015 HD re-release
Due to Dusklight being based on the original 2001 Gamecube release, the controls may not map very well to modern controllers. There are additional mods that port the more standardized Wii U HD release's controls to Dusklight with some catches.
The only fully-featured mod that can remap controller glyphs to different layouts is to use Dawnlight (a fork of Dusklight) that gives three equipment slots like the 2015 HD re-release, along with HATenshi's Wii U-like preset UI mod that gives comprehensive remapping visuals to match all player types to all controller types.